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Metformin Ameliorates Hepatic Steatosis and Inflammation without Altering Adipose Phenotype in Diet-Induced Obesity
Non-alcoholic fatty liver disease (NAFLD) is closely associated with obesity and insulin resistance. To better understand the pathophysiology of obesity-associated NAFLD, the present study examined the involvement of liver and adipose tissues in metformin actions on reducing hepatic steatosis and in...
Autores principales: | Woo, Shih-Lung, Xu, Hang, Li, Honggui, Zhao, Yan, Hu, Xiang, Zhao, Jiajia, Guo, Xin, Guo, Ting, Botchlett, Rachel, Qi, Ting, Pei, Ya, Zheng, Juan, Xu, Yiming, An, Xiaofei, Chen, Lulu, Chen, Lili, Li, Qifu, Xiao, Xiaoqiu, Huo, Yuqing, Wu, Chaodong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956460/ https://www.ncbi.nlm.nih.gov/pubmed/24638078 http://dx.doi.org/10.1371/journal.pone.0091111 |
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