ATM regulates Cdt1 stability during the unperturbed S phase to prevent re-replication

Ataxia-telangiectasia mutated (ATM) plays crucial roles in DNA damage responses, especially with regard to DNA double-strand breaks (DSBs). However, it appears that ATM can be activated not only by DSB, but also by some changes in chromatin architecture, suggesting potential ATM function in cell cyc...

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Detalles Bibliográficos
Autores principales: Iwahori, Satoko, Kohmon, Daisuke, Kobayashi, Junya, Tani, Yuhei, Yugawa, Takashi, Komatsu, Kenshi, Kiyono, Tohru, Sugimoto, Nozomi, Fujita, Masatoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956543/
https://www.ncbi.nlm.nih.gov/pubmed/24280901
http://dx.doi.org/10.4161/cc.27274

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