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HIV-1 Infected Peripheral Blood Mononuclear Cells Modulate the Fibrogenic Activity of Hepatic Stellate Cells through Secreted TGF-β and JNK Signaling

BACKGROUND AND AIMS: Patients with liver disease infected with the human immunodeficiency virus (HIV) exhibit accelerated progression of hepatic fibrosis and liver cirrhosis compared to uninfected individuals. We studied the effects of soluble factors secreted by HIV-infected peripheral blood mononu...

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Detalles Bibliográficos
Autores principales:	Gupta, Deepti, Rani, Manjusha, Khan, Nabab, Jameel, Shahid
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956633/ https://www.ncbi.nlm.nih.gov/pubmed/24637780 http://dx.doi.org/10.1371/journal.pone.0091569

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