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Crystal structures of the A(2A) adenosine receptor and their use in medicinal chemistry
New insights into drug design are derived from the X-ray crystallographic structures of G protein-coupled receptors (GPCRs), and the adenosine receptors (ARs) are at the forefront of this effort. The 3D knowledge of receptor binding and activation promises to enable drug discovery for GPCRs in gener...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer Berlin Heidelberg
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956660/ https://www.ncbi.nlm.nih.gov/pubmed/24660138 http://dx.doi.org/10.1186/2193-9616-1-22 |