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Anti-Platelet Therapy with Clopidogrel Prevents Endothelial Dysfunction and Vascular Remodeling in Aortas from Hypertensive Rats

The aim was to investigate the beneficial effects of clopidogrel in thoracic aorta function and structure and to characterize if P2Y(12) receptors contribute to these effects. Male Sprague Dawley rats were infused with angiotensin II [(Ang II) 60 ng.min(−1), 14 days] or saline (control rats) and wer...

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Detalles Bibliográficos
Autores principales:	Giachini, Fernanda R., Leite, Romulo, Osmond, David A., Lima, Victor V., Inscho, Edward W., Webb, R. Clinton, Tostes, Rita C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956760/ https://www.ncbi.nlm.nih.gov/pubmed/24638017 http://dx.doi.org/10.1371/journal.pone.0091890

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