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Cerebrospinal Fluid Biomarker and Brain Biopsy Findings in Idiopathic Normal Pressure Hydrocephalus

BACKGROUND: The significance of amyloid precursor protein (APP) and neuroinflammation in idiopathic normal pressure hydrocephalus (iNPH) and Alzheimer's disease (AD) is unknown. OBJECTIVE: To investigate the role of soluble APP (sAPP) and amyloid beta (Aβ) isoforms, proinflammatory cytokines, a...

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Detalles Bibliográficos
Autores principales:	Pyykkö, Okko T., Lumela, Miikka, Rummukainen, Jaana, Nerg, Ossi, Seppälä, Toni T., Herukka, Sanna-Kaisa, Koivisto, Anne M., Alafuzoff, Irina, Puli, Lakshman, Savolainen, Sakari, Soininen, Hilkka, Jääskeläinen, Juha E., Hiltunen, Mikko, Zetterberg, Henrik, Leinonen, Ville
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956805/ https://www.ncbi.nlm.nih.gov/pubmed/24638077 http://dx.doi.org/10.1371/journal.pone.0091974

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