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DNA Conformational Transitions Induced by Supercoiling Control Transcription in Chromatin
Regulation of transcription in eukaryotes is considered in the light of recent findings demonstrating the presence of negative and positive superhelical tension in chromatin. This tension induces conformational transitions in DNA duplex. Particularly, the transition into A-form renders DNA accessibl...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Libertas Academica
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956857/ https://www.ncbi.nlm.nih.gov/pubmed/24653646 http://dx.doi.org/10.4137/GRSB.S13756 |