Cargando…
Discovery of Novel Ligands for Mouse Olfactory Receptor MOR42-3 Using an In Silico Screening Approach and In Vitro Validation
The ligands for many olfactory receptors remain largely unknown despite successful heterologous expression of these receptors. Understanding the molecular receptive range of olfactory receptors and deciphering the olfactory recognition code are hampered by the huge number of odorants and large numbe...
Autores principales: | Bavan, Selvan, Sherman, Benjamin, Luetje, Charles W., Abaffy, Tatjana |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956865/ https://www.ncbi.nlm.nih.gov/pubmed/24637889 http://dx.doi.org/10.1371/journal.pone.0092064 |
Ejemplares similares
-
The location of olfactory receptors within olfactory epithelium is independent of odorant volatility and solubility
por: Abaffy, Tatjana, et al.
Publicado: (2011) -
The extremely broad odorant response profile of mouse olfactory sensory neurons expressing the odorant receptor MOR256‐17 includes trace amine‐associated receptor ligands
por: Tazir, Bassim, et al.
Publicado: (2016) -
Role of efficacy as a determinant of locomotor activation by mu‐opioid receptor (MOR) ligands in female and male mice. II. Effects of novel MOR‐selective phenylmorphans with high‐to‐low MOR efficacy
por: Santos, Edna J., et al.
Publicado: (2023) -
Sex steroid hormone synthesis, metabolism, and the effects on the mammalian olfactory system
por: Abaffy, Tatjana, et al.
Publicado: (2022) -
GLUT3 inhibitor discovery through in silico ligand screening and in vivo validation in eukaryotic expression systems
por: Iancu, Cristina V., et al.
Publicado: (2022)