BikDDA, a Mutant of Bik with Longer Half-Life Expression Protein, Can Be a Novel Therapeutic Gene for Triple-Negative Breast Cancer

Our previous studies showed that BikDD, a constitutively active mutant form of Bik, exhibited powerful antitumor effects in preclinical pancreatic, lung and breast cancer models. Howerver, the antitumor activity of BikDD in triple-negative breast cancer (TNBC) is unknown. Here we show that aberrant...

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Detalles Bibliográficos
Autores principales: Jiao, Shiping, Wu, Minqing, Ye, Feng, Tang, Hailin, Xie, Xinhua, Xie, Xiaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956915/
https://www.ncbi.nlm.nih.gov/pubmed/24637719
http://dx.doi.org/10.1371/journal.pone.0092172

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956915/
https://www.ncbi.nlm.nih.gov/pubmed/24637719
http://dx.doi.org/10.1371/journal.pone.0092172

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