Three-Dimensional Lung Tumor Microenvironment Modulates Therapeutic Compound Responsiveness In Vitro – Implication for Drug Development

Three-dimensional (3D) cell culture is gaining acceptance in response to the need for cellular models that better mimic physiologic tissues. Spheroids are one such 3D model where clusters of cells will undergo self-assembly to form viable, 3D tumor-like structures. However, to date little is known a...

Descripción completa

Detalles Bibliográficos
Autores principales: Ekert, Jason E., Johnson, Kjell, Strake, Brandy, Pardinas, Jose, Jarantow, Stephen, Perkinson, Robert, Colter, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956916/
https://www.ncbi.nlm.nih.gov/pubmed/24638075
http://dx.doi.org/10.1371/journal.pone.0092248

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956916/
https://www.ncbi.nlm.nih.gov/pubmed/24638075
http://dx.doi.org/10.1371/journal.pone.0092248

Ejemplares similares