Ocular Graft Versus Host Disease Following Allogeneic Stem Cell Transplantation: A Review of Current Knowledge and Recommendations

Graft versus host disease (GVHD) is a common complication of allogeneic stem cell transplantation (allo-SCT). Ocular GVHD develops in approximately 40-60% of patients following allo-SCT and its most common clinical manifestations include keratoconjunctivitis sicca and cicatricial conjunctivitis. Ocu...

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Autores principales: Nassiri, Nariman, Eslani, Medi, Panahi, Nekoo, Mehravaran, Shiva, Ziaei, Alireza, Djalilian, Ali R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ophthalmic Research Center 2013
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3957042/
https://www.ncbi.nlm.nih.gov/pubmed/24653823
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author Nassiri, Nariman
Eslani, Medi
Panahi, Nekoo
Mehravaran, Shiva
Ziaei, Alireza
Djalilian, Ali R.
author_facet Nassiri, Nariman
Eslani, Medi
Panahi, Nekoo
Mehravaran, Shiva
Ziaei, Alireza
Djalilian, Ali R.
author_sort Nassiri, Nariman
collection PubMed
description Graft versus host disease (GVHD) is a common complication of allogeneic stem cell transplantation (allo-SCT). Ocular GVHD develops in approximately 40-60% of patients following allo-SCT and its most common clinical manifestations include keratoconjunctivitis sicca and cicatricial conjunctivitis. Ocular GVHD may lead to severe ocular surface disease, which can significantly diminish quality of life and restrict daily activities. It is thus important to monitor the condition closely since with timely diagnosis, irreversible damage can be avoided. The current review will focus on updated information regarding ocular GVHD.
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spelling pubmed-39570422014-03-20 Ocular Graft Versus Host Disease Following Allogeneic Stem Cell Transplantation: A Review of Current Knowledge and Recommendations Nassiri, Nariman Eslani, Medi Panahi, Nekoo Mehravaran, Shiva Ziaei, Alireza Djalilian, Ali R. J Ophthalmic Vis Res Review Article Graft versus host disease (GVHD) is a common complication of allogeneic stem cell transplantation (allo-SCT). Ocular GVHD develops in approximately 40-60% of patients following allo-SCT and its most common clinical manifestations include keratoconjunctivitis sicca and cicatricial conjunctivitis. Ocular GVHD may lead to severe ocular surface disease, which can significantly diminish quality of life and restrict daily activities. It is thus important to monitor the condition closely since with timely diagnosis, irreversible damage can be avoided. The current review will focus on updated information regarding ocular GVHD. Ophthalmic Research Center 2013-10 /pmc/articles/PMC3957042/ /pubmed/24653823 Text en © 2013 Ophthalmic Research Center, Shahid Beheshti University of Medical Sciences http://creativecommons.org/licenses/by-nc/3.0/ This work is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly.
spellingShingle Review Article
Nassiri, Nariman
Eslani, Medi
Panahi, Nekoo
Mehravaran, Shiva
Ziaei, Alireza
Djalilian, Ali R.
Ocular Graft Versus Host Disease Following Allogeneic Stem Cell Transplantation: A Review of Current Knowledge and Recommendations
title Ocular Graft Versus Host Disease Following Allogeneic Stem Cell Transplantation: A Review of Current Knowledge and Recommendations
title_full Ocular Graft Versus Host Disease Following Allogeneic Stem Cell Transplantation: A Review of Current Knowledge and Recommendations
title_fullStr Ocular Graft Versus Host Disease Following Allogeneic Stem Cell Transplantation: A Review of Current Knowledge and Recommendations
title_full_unstemmed Ocular Graft Versus Host Disease Following Allogeneic Stem Cell Transplantation: A Review of Current Knowledge and Recommendations
title_short Ocular Graft Versus Host Disease Following Allogeneic Stem Cell Transplantation: A Review of Current Knowledge and Recommendations
title_sort ocular graft versus host disease following allogeneic stem cell transplantation: a review of current knowledge and recommendations
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3957042/
https://www.ncbi.nlm.nih.gov/pubmed/24653823
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