Metformin Plays a Dual Role in MIN6 Pancreatic β Cell Function through AMPK-dependent Autophagy

Metformin improves insulin sensitivity in insulin sensitive tissues such as liver, muscle and fat. However, the functional roles and the underlying mechanism of metformin action in pancreatic β cells remain elusive. Here we show that, under normal growth condition, metformin suppresses MIN6 β cell p...

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Detalles Bibliográficos
Autores principales: Jiang, Yingling, Huang, Wei, Wang, Jing, Xu, Zhipeng, He, Jieyu, Lin, Xiaohong, Zhou, Zhiguang, Zhang, Jingjing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3957082/
https://www.ncbi.nlm.nih.gov/pubmed/24644425
http://dx.doi.org/10.7150/ijbs.7929

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