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Role of Tet1 in genomic imprinting erasure
Genomic imprinting is an allele-specific gene expression system important for mammalian development and function (1). The molecular basis of genomic imprinting is allele-specific DNA methylation (1,2). While it is well known that the de novo DNA methyltransferases Dnmt3a/b are responsible for the es...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3957231/ https://www.ncbi.nlm.nih.gov/pubmed/24291790 http://dx.doi.org/10.1038/nature12805 |