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Role of Tet1 in genomic imprinting erasure

Genomic imprinting is an allele-specific gene expression system important for mammalian development and function (1). The molecular basis of genomic imprinting is allele-specific DNA methylation (1,2). While it is well known that the de novo DNA methyltransferases Dnmt3a/b are responsible for the es...

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Detalles Bibliográficos
Autores principales: Yamaguchi, Shinpei, Shen, Li, Liu, Yuting, Sendler, Damian, Zhang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3957231/
https://www.ncbi.nlm.nih.gov/pubmed/24291790
http://dx.doi.org/10.1038/nature12805

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