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Rewiring the transcriptional regulatory circuits of cells

The molecular mechanisms that regulate gene expression can evolve either by changing the cis-acting DNA elements in promoters, or by replacing the trans-acting regulatory proteins. New data from yeast species show that both processes can happen.

Detalles Bibliográficos
Autores principales: Scannell, Devin R, Wolfe, Ken
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC395740/
https://www.ncbi.nlm.nih.gov/pubmed/14759249
Descripción
Sumario:The molecular mechanisms that regulate gene expression can evolve either by changing the cis-acting DNA elements in promoters, or by replacing the trans-acting regulatory proteins. New data from yeast species show that both processes can happen.