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High-Throughput Chemical Screening for Antivirulence Developmental Phenotypes in Trypanosoma brucei

In the bloodstream of mammalian hosts, the sleeping sickness parasite, Trypanosoma brucei, exists as a proliferative slender form or a nonproliferative, transmissible, stumpy form. The transition between these developmental forms is controlled by a density-dependent mechanism that is important for t...

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Detalles Bibliográficos
Autores principales:	MacGregor, Paula, Ivens, Alasdair, Shave, Steven, Collie, Iain, Gray, David, Auer, Manfred, Matthews, Keith R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2014
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3957582/ https://www.ncbi.nlm.nih.gov/pubmed/24442893 http://dx.doi.org/10.1128/EC.00335-13

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