The ABC transporter gene family of Caenorhabditis elegans has implications for the evolutionary dynamics of multidrug resistance in eukaryotes

BACKGROUND: Many drugs of natural origin are hydrophobic and can pass through cell membranes. Hydrophobic molecules must be susceptible to active efflux systems if they are to be maintained at lower concentrations in cells than in their environment. Multi-drug resistance (MDR), often mediated by int...

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Detalles Bibliográficos
Autores principales: Sheps, Jonathan A, Ralph, Steven, Zhao, Zhongying, Baillie, David L, Ling, Victor
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC395765/
https://www.ncbi.nlm.nih.gov/pubmed/15003118

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