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A seeded propagation of Cu, Zn-superoxide dismutase aggregates in amyotrophic lateral sclerosis
Abnormal accumulation of protein inclusions in motor neurons has been known as a major pathological change in amyotrophic lateral sclerosis (ALS). Increasing numbers of proteins including mutant Cu, Zn-superoxide dismutase (SOD1) have been identified as constituents of pathological inclusions in a f...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3957682/ https://www.ncbi.nlm.nih.gov/pubmed/24672430 http://dx.doi.org/10.3389/fncel.2014.00083 |