T-type calcium channel Ca(v)3.2 deficient mice show elevated anxiety, impaired memory and reduced sensitivity to psychostimulants

The fine-tuning of neuronal excitability relies on a tight control of Ca(2+) homeostasis. The low voltage-activated (LVA) T-type calcium channels (Ca(v)3.1, Ca(v)3.2 and Ca(v)3.3 isoforms) play a critical role in regulating these processes. Despite their wide expression throughout the central nervou...

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Detalles Bibliográficos
Autores principales: Gangarossa, Giuseppe, Laffray, Sophie, Bourinet, Emmanuel, Valjent, Emmanuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3957728/
https://www.ncbi.nlm.nih.gov/pubmed/24672455
http://dx.doi.org/10.3389/fnbeh.2014.00092

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3957728/
https://www.ncbi.nlm.nih.gov/pubmed/24672455
http://dx.doi.org/10.3389/fnbeh.2014.00092

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