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T-type calcium channel Ca(v)3.2 deficient mice show elevated anxiety, impaired memory and reduced sensitivity to psychostimulants
The fine-tuning of neuronal excitability relies on a tight control of Ca(2+) homeostasis. The low voltage-activated (LVA) T-type calcium channels (Ca(v)3.1, Ca(v)3.2 and Ca(v)3.3 isoforms) play a critical role in regulating these processes. Despite their wide expression throughout the central nervou...
Autores principales: | Gangarossa, Giuseppe, Laffray, Sophie, Bourinet, Emmanuel, Valjent, Emmanuel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3957728/ https://www.ncbi.nlm.nih.gov/pubmed/24672455 http://dx.doi.org/10.3389/fnbeh.2014.00092 |
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