The mammalian transcriptome and the function of non-coding DNA sequences

For decades, researchers have focused most of their attention on protein-coding genes and proteins. With the completion of the human and mouse genomes and the accumulation of data on the mammalian transcriptome, the focus now shifts to non-coding DNA sequences, RNA-coding genes and their transcripts...

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Detalles Bibliográficos
Autores principales: Shabalina, Svetlana A, Spiridonov, Nikolay A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Opinion
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC395773/
https://www.ncbi.nlm.nih.gov/pubmed/15059247
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author Shabalina, Svetlana A
Spiridonov, Nikolay A
author_facet Shabalina, Svetlana A
Spiridonov, Nikolay A
author_sort Shabalina, Svetlana A
collection PubMed
description For decades, researchers have focused most of their attention on protein-coding genes and proteins. With the completion of the human and mouse genomes and the accumulation of data on the mammalian transcriptome, the focus now shifts to non-coding DNA sequences, RNA-coding genes and their transcripts. Many non-coding transcribed sequences are proving to have important regulatory roles, but the functions of the majority remain mysterious.
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spelling pubmed-3957732004-04-24 The mammalian transcriptome and the function of non-coding DNA sequences Shabalina, Svetlana A Spiridonov, Nikolay A Genome Biol Opinion For decades, researchers have focused most of their attention on protein-coding genes and proteins. With the completion of the human and mouse genomes and the accumulation of data on the mammalian transcriptome, the focus now shifts to non-coding DNA sequences, RNA-coding genes and their transcripts. Many non-coding transcribed sequences are proving to have important regulatory roles, but the functions of the majority remain mysterious. BioMed Central 2004 2004-03-25 /pmc/articles/PMC395773/ /pubmed/15059247 Text en Copyright © 2004 BioMed Central Ltd
spellingShingle Opinion
Shabalina, Svetlana A
Spiridonov, Nikolay A
The mammalian transcriptome and the function of non-coding DNA sequences
title The mammalian transcriptome and the function of non-coding DNA sequences
title_full The mammalian transcriptome and the function of non-coding DNA sequences
title_fullStr The mammalian transcriptome and the function of non-coding DNA sequences
title_full_unstemmed The mammalian transcriptome and the function of non-coding DNA sequences
title_short The mammalian transcriptome and the function of non-coding DNA sequences
title_sort mammalian transcriptome and the function of non-coding dna sequences
topic Opinion
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC395773/
https://www.ncbi.nlm.nih.gov/pubmed/15059247
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