Enriching for direct regulatory targets in perturbed gene-expression profiles

Here we build on a previously proposed algorithm to infer direct regulatory relationships using gene-expression profiles from cells in which individual genes are deleted or overexpressed. The updated algorithm can process networks containing feedback loops, incorporate positive and negative regulato...

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Detalles Bibliográficos
Autores principales: Tringe, Susannah G, Wagner, Andreas, Ruby, Stephanie W
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC395788/
https://www.ncbi.nlm.nih.gov/pubmed/15059262

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