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Clavulanic acid production by the MMS 150 mutant obtained from wild type Streptomyces clavuligerus ATCC 27064
Clavulanic acid (CA) is a powerful inhibitor of the beta-lactamases, enzymes produced by bacteria resistants to penicillin and cefalosporin. This molecule is produced industrially by strains of Streptomyces clavuligerus in complex media which carbon and nitrogen resources are supplied by inexpensive...
Autores principales: | da Silva Vasconcelos, Eliton, de Lima, Vanderlei Aparecido, Goto, Leandro Seiji, Cruz-Hernández, Isara Lourdes, Hokka, Carlos Osamu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Brazilian Society of Microbiology
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958168/ https://www.ncbi.nlm.nih.gov/pubmed/24688492 http://dx.doi.org/10.1590/S1517-83822014005000005 |
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