Cargando…
Smart Materials Based on DNA Aptamers: Taking Aptasensing to the Next Level
“Smart” materials are an emerging category of multifunctional materials with physical or chemical properties that can be controllably altered in response to an external stimulus. By combining the standard properties of the advanced material with the unique ability to recognize and adapt in response...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Diversity Preservation International (MDPI)
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958272/ https://www.ncbi.nlm.nih.gov/pubmed/24553083 http://dx.doi.org/10.3390/s140203156 |
_version_ | 1782307839781371904 |
---|---|
author | Mastronardi, Emily Foster, Amanda Zhang, Xueru DeRosa, Maria C. |
author_facet | Mastronardi, Emily Foster, Amanda Zhang, Xueru DeRosa, Maria C. |
author_sort | Mastronardi, Emily |
collection | PubMed |
description | “Smart” materials are an emerging category of multifunctional materials with physical or chemical properties that can be controllably altered in response to an external stimulus. By combining the standard properties of the advanced material with the unique ability to recognize and adapt in response to a change in their environment, these materials are finding applications in areas such as sensing and drug delivery. While the majority of these materials are responsive to physical or chemical changes, a particularly exciting area of research seeks to develop smart materials that are sensitive to specific molecular or biomolecular stimuli. These systems require the integration of a molecular recognition probe specific to the target molecule of interest. The ease of synthesis and labeling, low cost, and stability of DNA aptamers make them uniquely suited to effectively serve as molecular recognition probes in novel smart material systems. This review will highlight current work in the area of aptamer-based smart materials and prospects for their future applications. |
format | Online Article Text |
id | pubmed-3958272 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Molecular Diversity Preservation International (MDPI) |
record_format | MEDLINE/PubMed |
spelling | pubmed-39582722014-03-20 Smart Materials Based on DNA Aptamers: Taking Aptasensing to the Next Level Mastronardi, Emily Foster, Amanda Zhang, Xueru DeRosa, Maria C. Sensors (Basel) Review “Smart” materials are an emerging category of multifunctional materials with physical or chemical properties that can be controllably altered in response to an external stimulus. By combining the standard properties of the advanced material with the unique ability to recognize and adapt in response to a change in their environment, these materials are finding applications in areas such as sensing and drug delivery. While the majority of these materials are responsive to physical or chemical changes, a particularly exciting area of research seeks to develop smart materials that are sensitive to specific molecular or biomolecular stimuli. These systems require the integration of a molecular recognition probe specific to the target molecule of interest. The ease of synthesis and labeling, low cost, and stability of DNA aptamers make them uniquely suited to effectively serve as molecular recognition probes in novel smart material systems. This review will highlight current work in the area of aptamer-based smart materials and prospects for their future applications. Molecular Diversity Preservation International (MDPI) 2014-02-18 /pmc/articles/PMC3958272/ /pubmed/24553083 http://dx.doi.org/10.3390/s140203156 Text en © 2014 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). |
spellingShingle | Review Mastronardi, Emily Foster, Amanda Zhang, Xueru DeRosa, Maria C. Smart Materials Based on DNA Aptamers: Taking Aptasensing to the Next Level |
title | Smart Materials Based on DNA Aptamers: Taking Aptasensing to the Next Level |
title_full | Smart Materials Based on DNA Aptamers: Taking Aptasensing to the Next Level |
title_fullStr | Smart Materials Based on DNA Aptamers: Taking Aptasensing to the Next Level |
title_full_unstemmed | Smart Materials Based on DNA Aptamers: Taking Aptasensing to the Next Level |
title_short | Smart Materials Based on DNA Aptamers: Taking Aptasensing to the Next Level |
title_sort | smart materials based on dna aptamers: taking aptasensing to the next level |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958272/ https://www.ncbi.nlm.nih.gov/pubmed/24553083 http://dx.doi.org/10.3390/s140203156 |
work_keys_str_mv | AT mastronardiemily smartmaterialsbasedondnaaptamerstakingaptasensingtothenextlevel AT fosteramanda smartmaterialsbasedondnaaptamerstakingaptasensingtothenextlevel AT zhangxueru smartmaterialsbasedondnaaptamerstakingaptasensingtothenextlevel AT derosamariac smartmaterialsbasedondnaaptamerstakingaptasensingtothenextlevel |