The extracellular matrix, p53 and estrogen compete to regulate cell-surface Fas/Apo-1 suicide receptor expression in proliferating embryonic cerebral cortical precursors, and reciprocally, Fas-ligand modifies estrogen control of cell-cycle proteins

BACKGROUND: Apoptosis is important for normal cerebral cortical development. We previously showed that the Fas suicide receptor was expressed within the developing cerebral cortex, and that in vitro Fas activation resulted in caspase-dependent death. Alterations in cell-surface Fas expression may si...

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Detalles Bibliográficos
Autores principales: Cheema, Zulfiqar F, Santillano, Daniel R, Wade, Stephen B, Newman, Joseph M, Miranda, Rajesh C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC395829/
https://www.ncbi.nlm.nih.gov/pubmed/15038834
http://dx.doi.org/10.1186/1471-2202-5-11

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