VEGF-B: a more balanced approach toward cardiac neovascularization?

There is an urgent need for new pharmacologic approaches to combat the clinical consequences of ischemic cardiomyopathy. In this issue of EMBO Molecular Medicine, Kivelä et al show that transgenic expression of VEGF-B in the rat heart leads to expansion of the coronary arterial tree and an increase...

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Detalles Bibliográficos
Autores principales: Kupatt, Christian, Hinkel, Rabea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958304/
https://www.ncbi.nlm.nih.gov/pubmed/24521742
http://dx.doi.org/10.1002/emmm.201303730
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author Kupatt, Christian
Hinkel, Rabea
author_facet Kupatt, Christian
Hinkel, Rabea
author_sort Kupatt, Christian
collection PubMed
description There is an urgent need for new pharmacologic approaches to combat the clinical consequences of ischemic cardiomyopathy. In this issue of EMBO Molecular Medicine, Kivelä et al show that transgenic expression of VEGF-B in the rat heart leads to expansion of the coronary arterial tree and an increase in functional coronary reserve, accompanied by a shift in myocardial metabolism from fatty acid to glucose utilization. See also: R Kivelä et al (March 2014)
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spelling pubmed-39583042014-03-31 VEGF-B: a more balanced approach toward cardiac neovascularization? Kupatt, Christian Hinkel, Rabea EMBO Mol Med Closeup There is an urgent need for new pharmacologic approaches to combat the clinical consequences of ischemic cardiomyopathy. In this issue of EMBO Molecular Medicine, Kivelä et al show that transgenic expression of VEGF-B in the rat heart leads to expansion of the coronary arterial tree and an increase in functional coronary reserve, accompanied by a shift in myocardial metabolism from fatty acid to glucose utilization. See also: R Kivelä et al (March 2014) Blackwell Publishing Ltd 2014-03 2014-02-12 /pmc/articles/PMC3958304/ /pubmed/24521742 http://dx.doi.org/10.1002/emmm.201303730 Text en © 2014 The Authors. http://creativecommons.org/licenses/by/3.0/ This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Closeup
Kupatt, Christian
Hinkel, Rabea
VEGF-B: a more balanced approach toward cardiac neovascularization?
title VEGF-B: a more balanced approach toward cardiac neovascularization?
title_full VEGF-B: a more balanced approach toward cardiac neovascularization?
title_fullStr VEGF-B: a more balanced approach toward cardiac neovascularization?
title_full_unstemmed VEGF-B: a more balanced approach toward cardiac neovascularization?
title_short VEGF-B: a more balanced approach toward cardiac neovascularization?
title_sort vegf-b: a more balanced approach toward cardiac neovascularization?
topic Closeup
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958304/
https://www.ncbi.nlm.nih.gov/pubmed/24521742
http://dx.doi.org/10.1002/emmm.201303730
work_keys_str_mv AT kupattchristian vegfbamorebalancedapproachtowardcardiacneovascularization
AT hinkelrabea vegfbamorebalancedapproachtowardcardiacneovascularization

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