Use of the heteroduplex mobility assay and cell sorting to select genome sequences of the CCR5 gene in HEK 293T cells edited by transcription activator-like effector nucleases

Engineered nucleases such as zinc finger nucleases (ZFN) and transcription activator-like effector nucleases (TALEN) are one of the most promising tools for modifying genomes. These site-specific enzymes cause double-strand breaks that allow gene disruption or gene insertion, thereby facilitating ge...

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Detalles Bibliográficos
Autores principales: Nerys-Junior, Arildo, Costa, Lendel C., Braga-Dias, Luciene P., Oliveira, Márcia, Rossi, Átila D., da Cunha, Rodrigo Delvecchio, Gonçalves, Gabriel S., Tanuri, Amilcar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Genética 2014
Materias:
Cellular, Molecular and Developmental Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958318/
https://www.ncbi.nlm.nih.gov/pubmed/24688299

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