Microvesicular Caspase-1 Mediates Lymphocyte Apoptosis in Sepsis

OBJECTIVE: Immune dysregulation during sepsis is poorly understood, however, lymphocyte apoptosis has been shown to correlate with poor outcomes in septic patients. The inflammasome, a molecular complex which includes caspase-1, is essential to the innate immune response to infection and also import...

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Detalles Bibliográficos
Autores principales: Exline, Matthew C., Justiniano, Steven, Hollyfield, Jennifer L., Berhe, Freweine, Besecker, Beth Y., Das, Srabani, Wewers, Mark D., Sarkar, Anasuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958341/
https://www.ncbi.nlm.nih.gov/pubmed/24643116
http://dx.doi.org/10.1371/journal.pone.0090968

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