Network Models Predict that Reduced Excitatory Fluctuations Can Give Rise to Hippocampal Network Hyper-Excitability in MeCP2-Null Mice

Rett syndrome is a severe pediatric neurological disorder caused by loss of function mutations within the gene encoding methyl CpG-binding protein 2 (MeCP2). Although MeCP2 is expressed near ubiquitously, the primary pathophysiology of Rett syndrome stems from impairments of nervous system function....

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Detalles Bibliográficos
Autores principales: Ho, Ernest C. Y., Eubanks, James H., Zhang, Liang, Skinner, Frances K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958347/
https://www.ncbi.nlm.nih.gov/pubmed/24642514
http://dx.doi.org/10.1371/journal.pone.0091148

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958347/
https://www.ncbi.nlm.nih.gov/pubmed/24642514
http://dx.doi.org/10.1371/journal.pone.0091148

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