A New Stochastic Model for Subgenomic Hepatitis C Virus Replication Considers Drug Resistant Mutants

As an RNA virus, hepatitis C virus (HCV) is able to rapidly acquire drug resistance, and for this reason the design of effective anti-HCV drugs is a real challenge. The HCV subgenomic replicon-containing cells are widely used for experimental studies of the HCV genome replication mechanisms, for dru...

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Detalles Bibliográficos
Autores principales: Ivanisenko, Nikita V., Mishchenko, Elena L., Akberdin, Ilya R., Demenkov, Pavel S., Likhoshvai, Vitaly A., Kozlov, Konstantin N., Todorov, Dmitry I., Gursky, Vitaly V., Samsonova, Maria G., Samsonov, Alexander M., Clausznitzer, Diana, Kaderali, Lars, Kolchanov, Nikolay A., Ivanisenko, Vladimir A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958367/
https://www.ncbi.nlm.nih.gov/pubmed/24643004
http://dx.doi.org/10.1371/journal.pone.0091502

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958367/
https://www.ncbi.nlm.nih.gov/pubmed/24643004
http://dx.doi.org/10.1371/journal.pone.0091502

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