Residues Essential for Panton-Valentine Leukocidin S Component Binding to Its Cell Receptor Suggest Both Plasticity and Adaptability in Its Interaction Surface

Panton-Valentine leukocidin (PVL), a bicomponent staphylococcal leukotoxin, is involved in the poor prognosis of necrotizing pneumonia. The present study aimed to elucidate the binding mechanism of PVL and in particular its cell-binding domain. The class S component of PVL, LukS-PV, is known to ensu...

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Detalles Bibliográficos
Autores principales: Laventie, Benoit-Joseph, Guérin, Frédéric, Mourey, Lionel, Tawk, Mira Y., Jover, Emmanuel, Maveyraud, Laurent, Prévost, Gilles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958440/
https://www.ncbi.nlm.nih.gov/pubmed/24643034
http://dx.doi.org/10.1371/journal.pone.0092094

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