Knockdown of GRP78 Promotes Apoptosis in Pancreatic Acinar Cells and Attenuates the Severity of Cerulein and LPS Induced Pancreatic Inflammation

Acute pancreatitis (AP) is a potentially lethal disease characterized by inflammation and parenchymal cell death; also, the severity of AP correlates directly with necrosis and inversely with apoptosis. However, mechanisms of regulating cell death in AP remain unclear. The endoplasmic reticulum (ER)...

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Detalles Bibliográficos
Autores principales: Liu, Yong, Yang, Lie, Chen, Ke-Ling, Zhou, Bin, Yan, Hui, Zhou, Zong-Guang, Li, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958537/
https://www.ncbi.nlm.nih.gov/pubmed/24643222
http://dx.doi.org/10.1371/journal.pone.0092389

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