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Survival Benefit of Traditional Chinese Herbal Medicine (A Herbal Formula for Invigorating Spleen) in Gastric Cancer Patients with Peritoneal Metastasis

Objective. We evaluated the efficiency of traditional Chinese herbal medicine (a compound herbal formula for invigorating spleen) as a complementary and alternative therapy for gastric cancer patients with peritoneal metastasis. Methods. Between 2001 and 2012, 93 gastric cancer patients with periton...

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Autores principales: Zhao, Lu, Zhao, Ai-Guang, Zhao, Gang, Xu, Yan, Zhu, Xiao-Hong, Cao, Ni-Da, Zheng, Jian, Yang, Jin-Kun, Xu, Jian-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958679/
https://www.ncbi.nlm.nih.gov/pubmed/24723961
http://dx.doi.org/10.1155/2014/625493
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author Zhao, Lu
Zhao, Ai-Guang
Zhao, Gang
Xu, Yan
Zhu, Xiao-Hong
Cao, Ni-Da
Zheng, Jian
Yang, Jin-Kun
Xu, Jian-Hua
author_facet Zhao, Lu
Zhao, Ai-Guang
Zhao, Gang
Xu, Yan
Zhu, Xiao-Hong
Cao, Ni-Da
Zheng, Jian
Yang, Jin-Kun
Xu, Jian-Hua
author_sort Zhao, Lu
collection PubMed
description Objective. We evaluated the efficiency of traditional Chinese herbal medicine (a compound herbal formula for invigorating spleen) as a complementary and alternative therapy for gastric cancer patients with peritoneal metastasis. Methods. Between 2001 and 2012, 93 gastric cancer patients with peritoneal metastasis were enrolled in this study. The effect of traditional Chinese herbal medicine on their long-term outcome was investigated. Kaplan-Meier method was used to assess the difference in survival time, and Cox proportional hazards regression analysis was performed to identify independent prognostic factors. Result. First-line palliative chemotherapy plus traditional Chinese herbal medicine was performed in 47 patients and the other 46 patients received chemotherapy alone. The overall survival was different between patients with and without traditional Chinese herbal medicine (12.0 versus 10.5 months; P = 0.046). According to the Cox proportional hazard model, first-line chemotherapy cycle (hazards ratio [HR] = 0.527; 95% CI = 0.323~0.860) and TCHM (hazards ratio [HR] = 0.644; 95% CI = 0.481~0.992) were selected as independent prognostic factors for survival. Conclusion. The results suggest that traditional Chinese herbal medicine could improve the prognosis of the gastric cancer patients with peritoneal metastasis.
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spelling pubmed-39586792014-04-10 Survival Benefit of Traditional Chinese Herbal Medicine (A Herbal Formula for Invigorating Spleen) in Gastric Cancer Patients with Peritoneal Metastasis Zhao, Lu Zhao, Ai-Guang Zhao, Gang Xu, Yan Zhu, Xiao-Hong Cao, Ni-Da Zheng, Jian Yang, Jin-Kun Xu, Jian-Hua Evid Based Complement Alternat Med Research Article Objective. We evaluated the efficiency of traditional Chinese herbal medicine (a compound herbal formula for invigorating spleen) as a complementary and alternative therapy for gastric cancer patients with peritoneal metastasis. Methods. Between 2001 and 2012, 93 gastric cancer patients with peritoneal metastasis were enrolled in this study. The effect of traditional Chinese herbal medicine on their long-term outcome was investigated. Kaplan-Meier method was used to assess the difference in survival time, and Cox proportional hazards regression analysis was performed to identify independent prognostic factors. Result. First-line palliative chemotherapy plus traditional Chinese herbal medicine was performed in 47 patients and the other 46 patients received chemotherapy alone. The overall survival was different between patients with and without traditional Chinese herbal medicine (12.0 versus 10.5 months; P = 0.046). According to the Cox proportional hazard model, first-line chemotherapy cycle (hazards ratio [HR] = 0.527; 95% CI = 0.323~0.860) and TCHM (hazards ratio [HR] = 0.644; 95% CI = 0.481~0.992) were selected as independent prognostic factors for survival. Conclusion. The results suggest that traditional Chinese herbal medicine could improve the prognosis of the gastric cancer patients with peritoneal metastasis. Hindawi Publishing Corporation 2014 2014-03-02 /pmc/articles/PMC3958679/ /pubmed/24723961 http://dx.doi.org/10.1155/2014/625493 Text en Copyright © 2014 Lu Zhao et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Zhao, Lu
Zhao, Ai-Guang
Zhao, Gang
Xu, Yan
Zhu, Xiao-Hong
Cao, Ni-Da
Zheng, Jian
Yang, Jin-Kun
Xu, Jian-Hua
Survival Benefit of Traditional Chinese Herbal Medicine (A Herbal Formula for Invigorating Spleen) in Gastric Cancer Patients with Peritoneal Metastasis
title Survival Benefit of Traditional Chinese Herbal Medicine (A Herbal Formula for Invigorating Spleen) in Gastric Cancer Patients with Peritoneal Metastasis
title_full Survival Benefit of Traditional Chinese Herbal Medicine (A Herbal Formula for Invigorating Spleen) in Gastric Cancer Patients with Peritoneal Metastasis
title_fullStr Survival Benefit of Traditional Chinese Herbal Medicine (A Herbal Formula for Invigorating Spleen) in Gastric Cancer Patients with Peritoneal Metastasis
title_full_unstemmed Survival Benefit of Traditional Chinese Herbal Medicine (A Herbal Formula for Invigorating Spleen) in Gastric Cancer Patients with Peritoneal Metastasis
title_short Survival Benefit of Traditional Chinese Herbal Medicine (A Herbal Formula for Invigorating Spleen) in Gastric Cancer Patients with Peritoneal Metastasis
title_sort survival benefit of traditional chinese herbal medicine (a herbal formula for invigorating spleen) in gastric cancer patients with peritoneal metastasis
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958679/
https://www.ncbi.nlm.nih.gov/pubmed/24723961
http://dx.doi.org/10.1155/2014/625493
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