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Differences in the Composition of the Human Antibody Repertoire by B Cell Subsets in the Blood
The vast initial diversity of the antibody repertoire is generated centrally by means of a complex series of V(D)J gene rearrangement events, variation in the site of gene segment joining, and TdT catalyzed N-region addition. Although the diversity is great, close inspection has revealed distinct an...
Autores principales: | Mroczek, Eva Szymanska, Ippolito, Gregory C., Rogosch, Tobias, Hoi, Kam Hon, Hwangpo, Tracy A., Brand, Marsha G., Zhuang, Yingxin, Liu, Cun Ren, Schneider, David A., Zemlin, Michael, Brown, Elizabeth E., Georgiou, George, Schroeder, Harry W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958703/ https://www.ncbi.nlm.nih.gov/pubmed/24678310 http://dx.doi.org/10.3389/fimmu.2014.00096 |
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