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Cell-Based in Vitro Blood–Brain Barrier Model Can Rapidly Evaluate Nanoparticles’ Brain Permeability in Association with Particle Size and Surface Modification

The possibility of nanoparticle (NP) uptake to the human central nervous system is a major concern. Recent reports showed that in animal models, nanoparticles (NPs) passed through the blood–brain barrier (BBB). For the safe use of NPs, it is imperative to evaluate the permeability of NPs through the...

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Detalles Bibliográficos
Autores principales: Hanada, Sanshiro, Fujioka, Kouki, Inoue, Yuriko, Kanaya, Fumihide, Manome, Yoshinobu, Yamamoto, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958822/
https://www.ncbi.nlm.nih.gov/pubmed/24469316
http://dx.doi.org/10.3390/ijms15021812

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