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Mass Spectrometry Analysis Coupled with de novo Sequencing Reveals Amino Acid Substitutions in Nucleocapsid Protein from Influenza A Virus

Amino acid substitutions in influenza A virus are the main reasons for both antigenic shift and virulence change, which result from non-synonymous mutations in the viral genome. Nucleocapsid protein (NP), one of the major structural proteins of influenza virus, is responsible for regulation of viral...

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Detalles Bibliográficos
Autores principales: Li, Zijian, Sun, Wanchun, Wu, Donglin, Gao, Xiang, Sun, Ningning, Liu, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958862/
https://www.ncbi.nlm.nih.gov/pubmed/24521884
http://dx.doi.org/10.3390/ijms15022465