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Dual Agent Loaded PLGA Nanoparticles Enhanced Antitumor Activity in a Multidrug-Resistant Breast Tumor Eenograft Model

Multidrug-resistant breast cancers have limited and ineffective clinical treatment options. This study aimed to develop PLGA nanoparticles containing a synergistic combination of vincristine and verapamil to achieve less toxicity and enhanced efficacy on multidrug-resistant breast cancers. The 1:250...

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Detalles Bibliográficos
Autores principales: Chen, Yan, Zheng, Xue-Lian, Fang, Dai-Long, Yang, Yang, Zhang, Jin-Kun, Li, Hui-Li, Xu, Bei, Lei, Yi, Ren, Ke, Song, Xiang-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958880/
https://www.ncbi.nlm.nih.gov/pubmed/24552875
http://dx.doi.org/10.3390/ijms15022761