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Soluble Calreticulin Induces Tumor Necrosis Factor-α (TNF-α) and Interleukin (IL)-6 Production by Macrophages through Mitogen-Activated Protein Kinase (MAPK) and NFκB Signaling Pathways

We have recently reported that soluble calreticulin (CRT) accumulates in the sera of patients with rheumatoid arthritis or systemic lupus erythematosus. Moreover, following self-oligomerization, soluble recombinant CRT (rCRT) polypeptides exhibit potent immunostimulatory activities including macroph...

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Detalles Bibliográficos
Autores principales:	Duo, Cui-Cui, Gong, Fang-Yuan, He, Xiao-Yan, Li, Yan-Mei, Wang, Jun, Zhang, Jin-Ping, Gao, Xiao-Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Molecular Diversity Preservation International (MDPI) 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958890/ https://www.ncbi.nlm.nih.gov/pubmed/24566135 http://dx.doi.org/10.3390/ijms15022916

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