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Large-Scale Domain Motions and Pyridoxal-5′-Phosphate Assisted Radical Catalysis in Coenzyme B(12)-Dependent Aminomutases
Lysine 5,6-aminomutase (5,6-LAM) and ornithine 4,5-aminomutase (4,5-OAM) are two of the rare enzymes that use assistance of two vitamins as cofactors. These enzymes employ radical generating capability of coenzyme B(12) (5′-deoxyadenosylcobalamin, dAdoCbl) and ability of pyridoxal-5′-phosphate (PLP,...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Molecular Diversity Preservation International (MDPI)
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958899/ https://www.ncbi.nlm.nih.gov/pubmed/24562332 http://dx.doi.org/10.3390/ijms15023064 |