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Dynamin-Related Protein 1 Inhibitors Protect against Ischemic Toxicity through Attenuating Mitochondrial Ca2+ Uptake from Endoplasmic Reticulum Store in PC12 Cells

Intracellular calcium homeostasis disorder and mitochondrial dysfunction are involved in many acute and chronic brain diseases, including ischemic brain injury. An imbalance in mitochondrial fission and fusion is one of the most important structural abnormalities found in a large number of mitochond...

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Detalles Bibliográficos
Autores principales: Tian, Ye, Li, Bin, Shi, Wen-Zhen, Chang, Ming-Ze, Zhang, Ge-Juan, Di, Zheng-Li, Liu, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958904/
https://www.ncbi.nlm.nih.gov/pubmed/24566142
http://dx.doi.org/10.3390/ijms15023172