Thiopurine methyltransferase genotype and thiopurine S-methyltransferase activity in Greek children with inflammatory bowel disease

BACKGROUND: Azathioprine (AZA) and 6-mercaptopurine (6MP) are used in the treatment of pediatric inflammatory bowel disease (IBD). Genetic variations in thiopurine S-methyltranfarase (TPMT) gene have been correlated with enzyme activity and with the occurrence of adverse events to AZA and 6MP. The a...

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Detalles Bibliográficos
Autores principales: Gazouli, Μaria, Pachoula, Ioanna, Panayotou, Ioanna, Chouliaras, Georgios, Anagnou, Nicholas P., Chroussos, George, Roma, Eleftheria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hellenic Society of Gastroenterology 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959370/
https://www.ncbi.nlm.nih.gov/pubmed/24714152

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