Effectiveness of infliximab in the treatment of perianal fistulas in ulcerative colitis: report of two cases

Ulcerative colitis is a chronic inflammatory bowel disease of unknown etiopathogenesis and increasing incidence in recent years. Perianal complications of ulcerative colitis are rare and seem to be associated with higher extent of inflammation and a more severe course of the disease. The cases of tw...

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Autores principales: de la Piscina, Patricia Ramírez, Duca, Ileana, Estrada, Silvia, Spicakova, Katerina, Calderón, Rosario, Urtasun, Leire, Marra-López, Carlos, Salvador, Marta, Delgado, Elvira, Campos, Francisco García
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hellenic Society of Gastroenterology 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959434/
https://www.ncbi.nlm.nih.gov/pubmed/24714219
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author de la Piscina, Patricia Ramírez
Duca, Ileana
Estrada, Silvia
Spicakova, Katerina
Calderón, Rosario
Urtasun, Leire
Marra-López, Carlos
Salvador, Marta
Delgado, Elvira
Campos, Francisco García
author_facet de la Piscina, Patricia Ramírez
Duca, Ileana
Estrada, Silvia
Spicakova, Katerina
Calderón, Rosario
Urtasun, Leire
Marra-López, Carlos
Salvador, Marta
Delgado, Elvira
Campos, Francisco García
author_sort de la Piscina, Patricia Ramírez
collection PubMed
description Ulcerative colitis is a chronic inflammatory bowel disease of unknown etiopathogenesis and increasing incidence in recent years. Perianal complications of ulcerative colitis are rare and seem to be associated with higher extent of inflammation and a more severe course of the disease. The cases of two male patients with severe corticoid-dependent ulcerative colitis of protracted clinical course who developed perianal fistulas and abscesses successfully treated with infliximab are reported. Treatment with infliximab was followed by perianal fistula closure with marked improvement in the quality of life over 2-year follow-up period.
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spelling pubmed-39594342014-04-07 Effectiveness of infliximab in the treatment of perianal fistulas in ulcerative colitis: report of two cases de la Piscina, Patricia Ramírez Duca, Ileana Estrada, Silvia Spicakova, Katerina Calderón, Rosario Urtasun, Leire Marra-López, Carlos Salvador, Marta Delgado, Elvira Campos, Francisco García Ann Gastroenterol Case Report Ulcerative colitis is a chronic inflammatory bowel disease of unknown etiopathogenesis and increasing incidence in recent years. Perianal complications of ulcerative colitis are rare and seem to be associated with higher extent of inflammation and a more severe course of the disease. The cases of two male patients with severe corticoid-dependent ulcerative colitis of protracted clinical course who developed perianal fistulas and abscesses successfully treated with infliximab are reported. Treatment with infliximab was followed by perianal fistula closure with marked improvement in the quality of life over 2-year follow-up period. Hellenic Society of Gastroenterology 2013 /pmc/articles/PMC3959434/ /pubmed/24714219 Text en Copyright: © Hellenic Society of Gastroenterology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
de la Piscina, Patricia Ramírez
Duca, Ileana
Estrada, Silvia
Spicakova, Katerina
Calderón, Rosario
Urtasun, Leire
Marra-López, Carlos
Salvador, Marta
Delgado, Elvira
Campos, Francisco García
Effectiveness of infliximab in the treatment of perianal fistulas in ulcerative colitis: report of two cases
title Effectiveness of infliximab in the treatment of perianal fistulas in ulcerative colitis: report of two cases
title_full Effectiveness of infliximab in the treatment of perianal fistulas in ulcerative colitis: report of two cases
title_fullStr Effectiveness of infliximab in the treatment of perianal fistulas in ulcerative colitis: report of two cases
title_full_unstemmed Effectiveness of infliximab in the treatment of perianal fistulas in ulcerative colitis: report of two cases
title_short Effectiveness of infliximab in the treatment of perianal fistulas in ulcerative colitis: report of two cases
title_sort effectiveness of infliximab in the treatment of perianal fistulas in ulcerative colitis: report of two cases
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959434/
https://www.ncbi.nlm.nih.gov/pubmed/24714219
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