Patients with refractory gastroesophageal reflux disease: diagnostic tools

Patients with refractory to proton pump inhibitors (PPIs) gastroesophageal reflux disease (GERD) symptoms are approximately 40% and represent a very common problem in clinical practice. Many of these patients do not have GERD, but suffer from functional heartburn or hypersensitive esophagus. After t...

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Detalles Bibliográficos
Autores principales: Karamanolis, Georgios P., Sifrim, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hellenic Society of Gastroenterology 2013
Materias:
Invited Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959500/
https://www.ncbi.nlm.nih.gov/pubmed/24714297
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author Karamanolis, Georgios P.
Sifrim, Daniel
author_facet Karamanolis, Georgios P.
Sifrim, Daniel
author_sort Karamanolis, Georgios P.
collection PubMed
description Patients with refractory to proton pump inhibitors (PPIs) gastroesophageal reflux disease (GERD) symptoms are approximately 40% and represent a very common problem in clinical practice. Many of these patients do not have GERD, but suffer from functional heartburn or hypersensitive esophagus. After thorough clinical evaluation and failure of escalation of PPI dose, diagnostic investigations include endoscopy, esophageal manometry, pH testing, esophageal Bilitec and esophageal impedance with pH monitoring.
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spelling pubmed-39595002014-04-07 Patients with refractory gastroesophageal reflux disease: diagnostic tools Karamanolis, Georgios P. Sifrim, Daniel Ann Gastroenterol Invited Review Patients with refractory to proton pump inhibitors (PPIs) gastroesophageal reflux disease (GERD) symptoms are approximately 40% and represent a very common problem in clinical practice. Many of these patients do not have GERD, but suffer from functional heartburn or hypersensitive esophagus. After thorough clinical evaluation and failure of escalation of PPI dose, diagnostic investigations include endoscopy, esophageal manometry, pH testing, esophageal Bilitec and esophageal impedance with pH monitoring. Hellenic Society of Gastroenterology 2013 /pmc/articles/PMC3959500/ /pubmed/24714297 Text en Copyright: © Hellenic Society of Gastroenterology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Invited Review
Karamanolis, Georgios P.
Sifrim, Daniel
Patients with refractory gastroesophageal reflux disease: diagnostic tools
title Patients with refractory gastroesophageal reflux disease: diagnostic tools
title_full Patients with refractory gastroesophageal reflux disease: diagnostic tools
title_fullStr Patients with refractory gastroesophageal reflux disease: diagnostic tools
title_full_unstemmed Patients with refractory gastroesophageal reflux disease: diagnostic tools
title_short Patients with refractory gastroesophageal reflux disease: diagnostic tools
title_sort patients with refractory gastroesophageal reflux disease: diagnostic tools
topic Invited Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959500/
https://www.ncbi.nlm.nih.gov/pubmed/24714297
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