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Dysferlin Mediates the Cytoprotective Effects of TRAF2 Following Myocardial Ischemia Reperfusion Injury

BACKGROUND: We have demonstrated that tumor necrosis factor (TNF) receptor‐associated factor 2 (TRAF2), a scaffolding protein common to TNF receptors 1 and 2, confers cytoprotection in the heart. However, the mechanisms for the cytoprotective effects of TRAF2 are not known. METHODS/RESULTS: Mice wit...

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Detalles Bibliográficos
Autores principales: Tzeng, Huei‐Ping, Evans, Sarah, Gao, Feng, Chambers, Kari, Topkara, Veli K., Sivasubramanian, Natarajan, Barger, Philip M., Mann, Douglas L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959693/
https://www.ncbi.nlm.nih.gov/pubmed/24572254
http://dx.doi.org/10.1161/JAHA.113.000662