Role of Extracellular RNA and TLR3‐Trif Signaling in Myocardial Ischemia–Reperfusion Injury

BACKGROUND: Toll‐like receptor 3 (TLR3) was originally identified as the receptor for viral RNA and represents a major host antiviral defense mechanism. TLR3 may also recognize extracellular RNA (exRNA) released from injured tissues under certain stress conditions. However, a role for exRNA and TLR3...

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Detalles Bibliográficos
Autores principales: Chen, Chan, Feng, Yan, Zou, Lin, Wang, Larry, Chen, Howard H., Cai, Jia‐Yan, Xu, Jun‐Mei, Sosnovik, David E., Chao, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959703/
https://www.ncbi.nlm.nih.gov/pubmed/24390148
http://dx.doi.org/10.1161/JAHA.113.000683

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