Elimination of NADPH Oxidase Activity Promotes Reductive Stress and Sensitizes the Heart to Ischemic Injury

BACKGROUND: The NADPH oxidase family (Nox) produces reactive oxygen species by adding the electron donated by NADPH to oxygen. Excessive reactive oxygen species production under a variety of pathological conditions has been attributed to increased Nox activity. Here, we aimed at investigating the ro...

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Detalles Bibliográficos
Autores principales: Yu, Qiujun, Lee, Chi Fung, Wang, Wang, Karamanlidis, Georgios, Kuroda, Junya, Matsushima, Shouji, Sadoshima, Junichi, Tian, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959718/
https://www.ncbi.nlm.nih.gov/pubmed/24470522
http://dx.doi.org/10.1161/JAHA.113.000555

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