Monoamine oxidase A expression is suppressed in human cholangiocarcinoma via coordinated epigenetic and IL-6-driven events

OBJECTIVES: The secretion of dopamine and serotonin is increased in cholangiocarcinoma, which has growth-promoting effects. Monoamine oxidase A (MAOA), the degradation enzyme of serotonin and dopamine, is suppressed in cholangiocarcinoma via an unknown mechanism. The aims of this study were to (i) c...

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Detalles Bibliográficos
Autores principales: Huang, Li, Frampton, Gabriel, Rao, Arundhati, Zhang, Kun-song, Chen, Wei, Lai, Jia-ming, Yin, Xiao-yu, Walker, Kimberly, Culbreath, Brianne, Leyva-Illades, Dinorah, Quinn, Matthew, McMillin, Matthew, Bradley, Michelle, Liang, Li-Jian, DeMorrow, Sharon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959781/
https://www.ncbi.nlm.nih.gov/pubmed/22906985
http://dx.doi.org/10.1038/labinvest.2012.110

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