Frequent inactivating mutations of STAG2 in bladder cancer are associated with low tumour grade and stage and inversely related to chromosomal copy number changes

Inactivating mutations of STAG2 have been reported at low frequency in several cancers. In glioblastoma, the function of STAG2 has been related to maintenance of euploidy via its role in the cohesin complex. In a screen of a large series of bladder tumours and cell lines, we found inactivating mutat...

Descripción completa

Detalles Bibliográficos
Autores principales: Taylor, Claire F., Platt, Fiona M., Hurst, Carolyn D., Thygesen, Helene H., Knowles, Margaret A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959811/
https://www.ncbi.nlm.nih.gov/pubmed/24270882
http://dx.doi.org/10.1093/hmg/ddt589

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959811/
https://www.ncbi.nlm.nih.gov/pubmed/24270882
http://dx.doi.org/10.1093/hmg/ddt589

Ejemplares similares