Functional interaction of Parkinson's disease-associated LRRK2 with members of the dynamin GTPase superfamily

Mutations in LRRK2 cause autosomal dominant Parkinson's disease (PD). LRRK2 encodes a multi-domain protein containing GTPase and kinase domains, and putative protein–protein interaction domains. Familial PD mutations alter the GTPase and kinase activity of LRRK2 in vitro. LRRK2 is suggested to...

Descripción completa

Detalles Bibliográficos
Autores principales: Stafa, Klodjan, Tsika, Elpida, Moser, Roger, Musso, Alessandra, Glauser, Liliane, Jones, Amy, Biskup, Saskia, Xiong, Yulan, Bandopadhyay, Rina, Dawson, Valina L., Dawson, Ted M., Moore, Darren J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959816/
https://www.ncbi.nlm.nih.gov/pubmed/24282027
http://dx.doi.org/10.1093/hmg/ddt600

Ejemplares similares

Ejemplares similares