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EGF-Like-Domain-7 Is Required for VEGF-Induced Akt/ERK Activation and Vascular Tube Formation in an Ex Vivo Angiogenesis Assay
EGFL7 is a secreted angiogenic factor, which in contrast to the well-known secreted angiogenic molecules VEGF and FGF-2, is almost exclusively expressed by endothelial cells and may act in an autocrine fashion. Prior studies have shown EGFL7 to mediate its angiogenic effects by interfering with the...
Autores principales: | Takeuchi, Kimio, Yanai, Ryoji, Kumase, Fumiaki, Morizane, Yuki, Suzuki, Jun, Kayama, Maki, Brodowska, Katarzyna, Nakazawa, Mitsuru, Miller, Joan W., Connor, Kip M., Vavvas, Demetrios G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960138/ https://www.ncbi.nlm.nih.gov/pubmed/24647208 http://dx.doi.org/10.1371/journal.pone.0091849 |
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